PDB 2qmg

PDB Links
Overview

PDB Information

PDB	2QMG
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor. Iserloh, U., Pan, J., Stamford, A.W., Kennedy, M.E., Zhang, Q., Zhang, L., Parker, E.M., McHugh, N.A., Favreau, L., Strickland, C., Voigt, J. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2007-07-16
Resolution	1.890
CATH Insert Date	20 Mar, 2008

PDB Images (7)

Image of CATH 2qmg

2qmg

PDB 2qmg

Image of CATH 2qmgA

2qmgA

PDB Chain 2qmgA

Image of CATH 2qmgB

2qmgB

PDB Chain 2qmgB

Image of CATH 2qmgA01

2qmgA01

CATH Domain 2qmgA01

Image of CATH 2qmgA02

2qmgA02

CATH Domain 2qmgA02

Image of CATH 2qmgB01

2qmgB01

CATH Domain 2qmgB01

Image of CATH 2qmgB02

2qmgB02

CATH Domain 2qmgB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	20 Mar, 2008	Chopped
B	20 Mar, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2qmgA01	21 Mar, 2008	2.40.70.10	Assigned
2qmgA02	21 Mar, 2008	2.40.70.10	Assigned
2qmgB01	21 Mar, 2008	2.40.70.10	Assigned
2qmgB02	21 Mar, 2008	2.40.70.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1