PDB Information

PDB2PHB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor
Kohrt, J.T., Bigge, C.F., Bryant, J.W., Casimiro-Garcia, A., Chi, L., Cody, W.L., Dahring, T., Dudley, D.A., Filipski, K.J., Haarer, S., Heemstra, R., Janiczek, N., Narasimhan, L., McClanahan, T., Peterson, J.T., Sahasrabudhe, V., Schaum, R., Van Huis, C.A., Welch, K.M., Zhang, E., Leadley, R.J., Edmunds, J.J.
Chem.Biol.Drug Des.
HeaderBlood Clotting
Released2007-04-10
Resolution2.300
CATH Insert Date27 Mar, 2008

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 27 Mar, 2008 Chopped
B 27 Mar, 2008 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2phbA01 28 Mar, 2008 2.40.10.10 Assigned
2phbA02 28 Mar, 2008 2.40.10.10 Assigned
2phbB00 28 Mar, 2008 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
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