PDB 2p16

PDB Information

PDB2P16
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa.
Pinto, D.J., Orwat, M.J., Koch, S., Rossi, K.A., Alexander, R.S., Smallwood, A., Wong, P.C., Rendina, A.R., Luettgen, J.M., Knabb, R.M., He, K., Xin, B., Wexler, R.R., Lam, P.Y.
J.Med.Chem.
HeaderHydrolase
Released2007-03-02
Resolution2.300
CATH Insert Date07 Nov, 2007

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
L 08 Nov, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2p16A01 18 Nov, 2007 2.40.10.10 Assigned
2p16A02 18 Nov, 2007 2.40.10.10 Assigned
2p16L00 18 Nov, 2007 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X