PDB 2ozr

PDB Information

PDB2OZR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.
Johnson, A.R., Pavlovsky, A.G., Ortwine, D.F., Prior, F., Man, C.F., Bornemeier, D.A., Banotai, C.A., Mueller, W.T., McConnell, P., Yan, C., Baragi, V., Lesch, C., Roark, W.H., Wilson, M., Datta, K., Guzman, R., Han, H.K., Dyer, R.D.
J.Biol.Chem.
HeaderHydrolase
Released2007-02-27
Resolution2.300
CATH Insert Date26 Jul, 2007

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 26 Jul, 2007 Chopped
B 26 Jul, 2007 Chopped
C 26 Jul, 2007 Chopped
D 26 Jul, 2007 Chopped
E 26 Jul, 2007 Chopped
F 26 Jul, 2007 Chopped
G 26 Jul, 2007 Chopped
H 26 Jul, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2ozrA00 16 Aug, 2007 3.40.390.10 Assigned
2ozrB00 16 Aug, 2007 3.40.390.10 Assigned
2ozrC00 16 Aug, 2007 3.40.390.10 Assigned
2ozrD00 16 Aug, 2007 3.40.390.10 Assigned
2ozrE00 16 Aug, 2007 3.40.390.10 Assigned
2ozrF00 16 Aug, 2007 3.40.390.10 Assigned
2ozrG00 16 Aug, 2007 3.40.390.10 Assigned
2ozrH00 16 Aug, 2007 3.40.390.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3