PDB 2of4

PDB Information

PDB2OF4
MethodX-RAY DIFFRACTION
Host OrganismInsect cell
Gene SourceHomo sapiens
Primary Citation
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties.
Martin, M.W., Newcomb, J., Nunes, J.J., Bemis, J.E., McGowan, D.C., White, R.D., Buchanan, J.L., Dimauro, E.F., Boucher, C., Faust, T., Hsieh, F., Huang, X., Lee, J.H., Schneider, S., Turci, S.M., Zhu, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-01-02
Resolution2.700
CATH Insert Date28 Feb, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2of4A01 01 Apr, 2009 3.30.200.20 Assigned
2of4A02 01 Apr, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P06239 LCK_HUMAN Homo sapiens Tyrosine-protein kinase Lck