PDB Information

PDB2O8H
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceRattus norvegicus
Primary Citation
Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors
Chappie, T.A., Humphrey, J.M., Allen, M.P., Estep, K.G., Fox, C.B., Lebel, L.A., Liras, S., Marr, E.S., Menniti, F.S., Pandit, J., Schmidt, C.J., Tu, M., Williams, R.D., Yang, F.V.
J.Med.Chem.
HeaderHydrolase
Released2006-12-12
Resolution1.800
CATH Insert Date09 Jan, 2007

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2007 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2o8hA00 11 Aug, 2010 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9QYJ6 PDE10_RAT Rattus norvegicus cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A