PDB Information

PDB2NP8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.
Tari, L.W., Hoffman, I.D., Bensen, D.C., Hunter, M.J., Nix, J., Nelson, K.J., McRee, D.E., Swanson, R.V.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2006-10-26
Resolution2.250
CATH Insert Date07 Jan, 2007

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2np8A01 29 Oct, 2009 3.30.200.20 Assigned
2np8A02 29 Oct, 2009 Write scan list
2np8A03 29 Oct, 2009 Write scan list

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A