PDB Information

PDB2J4Z
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
Fancelli, D., Moll, J., Varasi, M., Bravo, R., Artico, R., Berta, D., Bindi, S., Cameron, A., Candiani, I., Cappella, P., Carpinelli, P., Croci, W., Forte, B., Giorgini, M.L., Klapwijk, J., Marsiglio, A., Pesenti, E., Rocchetti, M., Roletto, F., Severino, D., Soncini, C., Storici, P., Tonani, R., Zugnoni, P., Vianello, P.
J. Med. Chem.
HeaderTransferase
Released2006-09-08
Resolution2.000
CATH Insert Date16 Nov, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Nov, 2006 Chopped
B 16 Nov, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2j4zA01 15 Jul, 2007 3.30.200.20 Assigned
2j4zA02 15 Jul, 2007 1.10.510.10 Assigned
2j4zB01 14 Jul, 2007 3.30.200.20 Assigned
2j4zB02 14 Jul, 2007 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
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