PDB 2irw

PDB Information

PDB2IRW
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Patel, J.R., Shuai, Q., Dinges, J., Winn, M., Pliushchev, M., Fung, S., Monzon, K., Chiou, W., Wang, J., Pan, L., Wagaw, S., Engstrom, K., Kerdesky, F.A., Longenecker, K., Judge, R., Qin, W., Imade, H.M., Stolarik, D., Beno, D.W., Brune, M., Chovan, L.E., Sham, H.L., Jacobson, P., Link, J.T.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2006-10-16
Resolution3.100
CATH Insert Date23 Feb, 2007

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 23 Feb, 2007 Chopped
B 23 Feb, 2007 Chopped
C 23 Feb, 2007 Chopped
D 23 Feb, 2007 Chopped
E 23 Feb, 2007 Chopped
F 23 Feb, 2007 Chopped
G 23 Feb, 2007 Chopped
H 23 Feb, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2irwA00 05 Dec, 2008 3.40.50.720 Assigned
2irwB00 05 Dec, 2008 3.40.50.720 Assigned
2irwC00 05 Dec, 2008 3.40.50.720 Assigned
2irwD00 05 Dec, 2008 3.40.50.720 Assigned
2irwE00 05 Dec, 2008 3.40.50.720 Assigned
2irwF00 05 Dec, 2008 3.40.50.720 Assigned
2irwG00 05 Dec, 2008 3.40.50.720 Assigned
2irwH00 05 Dec, 2008 3.40.50.720 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1