PDB 2hxl

PDB Information

PDB2HXL
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.
Huang, S., Garbaccio, R.M., Fraley, M.E., Steen, J., Kreatsoulas, C., Hartman, G., Stirdivant, S., Drakas, B., Rickert, K., Walsh, E., Hamilton, K., Buser, C.A., Hardwick, J., Mao, X., Abrams, M., Beck, S., Tao, W., Lobell, R., Sepp-Lorenzino, L., Yan, Y., Ikuta, M., Murphy, J.Z., Sardana, V., Munshi, S., Kuo, L., Reilly, M., Mahan, E.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2006-08-03
Resolution1.800
CATH Insert Date21 Jun, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Jun, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2hxlA01 14 Jul, 2007 3.30.200.20 Assigned
2hxlA02 14 Jul, 2007 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1