PDB Information

PDB2H2Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceTrypanosoma cruzi
Primary Citation
Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
Schormann, N., Senkovich, O., Walker, K., Wright, D.L., Anderson, A.C., Rosowsky, A., Ananthan, S., Shinkre, B., Velu, S., Chattopadhyay, D.
Proteins
HeaderOxidoreductase, Transferase
Released2006-05-19
Resolution2.400
CATH Insert Date10 Apr, 2008

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Apr, 2008 Chopped
B 10 Apr, 2008 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2h2qA01 09 May, 2013 3.40.430.10 Assigned
2h2qA02 09 May, 2013 3.30.572.10 Assigned
2h2qB01 10 May, 2013 3.40.430.10 Assigned
2h2qB02 10 May, 2013 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
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