PDB 2ghg

PDB Information

PDB2GHG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Zhu, G.D., Gandhi, V.B., Gong, J., Luo, Y., Liu, X., Shi, Y., Guan, R., Magnone, S.R., Klinghofer, V., Johnson, E.F., Bouska, J., Shoemaker, A., Oleksijew, A., Jarvis, K., Park, C., De Jong, R., Oltersdorf, T., Li, Q., Rosenberg, S.H., Giranda, V.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2006-03-27
Resolution3.500
CATH Insert Date29 Mar, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Mar, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ghgA01 14 Jul, 2007 3.30.200.20 Assigned
2ghgA02 14 Jul, 2007 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1