PDB Information

PDB2G01
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors.
Liu, M., Xin, Z., Clampit, J.E., Wang, S., Gum, R.J., Haasch, D.L., Trevillyan, J.M., Abad-Zapatero, C., Fry, E.H., Sham, H.L., Liu, G.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2006-02-10
Resolution3.500
CATH Insert Date14 Jul, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
F 14 Jul, 2006 Rejected
G 14 Jul, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2g01A01 16 Oct, 2006 3.30.200.20 Assigned
2g01A02 16 Oct, 2006 1.10.510.10 Assigned
2g01B01 16 Oct, 2006 3.30.200.20 Assigned
2g01B02 16 Oct, 2006 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9UQF2 JIP1_HUMAN Homo sapiens C-Jun-amino-terminal kinase-interacting protein 1
P45983 MK08_HUMAN Homo sapiens Mitogen-activated protein kinase 8
Q9UQF2 JIP1_HUMAN Homo sapiens C-Jun-amino-terminal kinase-interacting protein 1
P45983 MK08_HUMAN Homo sapiens Mitogen-activated protein kinase 8
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