PDB 2fl2

PDB Information

PDB2FL2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP.
Fraley, M.E., Garbaccio, R.M., Arrington, K.L., Hoffman, W.F., Tasber, E.S., Coleman, P.J., Buser, C.A., Walsh, E.S., Hamilton, K., Fernandes, C., Schaber, M.D., Lobell, R.B., Tao, W., South, V.J., Yan, Y., Kuo, L.C., Prueksaritanont, T., Shu, C., Torrent, M., Heimbrook, D.C., Kohl, N.E., Huber, H.E., Hartman, G.D.
Bioorg.Med.Chem.Lett.
HeaderCell Cycle
Released2006-01-05
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2006 Chopped
B 15 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2fl2A00 17 Mar, 2006 3.40.850.10 Assigned
2fl2B00 17 Mar, 2006 3.40.850.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11