PDB Information

PDB2FHY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode.
von Geldern, T.W., Lai, C., Gum, R.J., Daly, M., Sun, C., Fry, E.H., Abad-Zapatero, C.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2005-12-27
Resolution2.950
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2006 Chopped
D 15 Mar, 2006 Chopped
H 15 Mar, 2006 Chopped
L 15 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2fhyA01 17 Mar, 2006 3.30.540.10 Assigned
2fhyA02 17 Mar, 2006 3.40.190.80 Assigned
2fhyD01 17 Mar, 2006 3.30.540.10 Assigned
2fhyD02 17 Mar, 2006 3.40.190.80 Assigned
2fhyH01 17 Mar, 2006 3.30.540.10 Assigned
2fhyH02 17 Mar, 2006 3.40.190.80 Assigned
2fhyL01 17 Mar, 2006 3.30.540.10 Assigned
2fhyL02 17 Mar, 2006 3.40.190.80 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09467 F16P1_HUMAN Homo sapiens Fructose-1,6-bisphosphatase 1
P09467 F16P1_HUMAN Homo sapiens Fructose-1,6-bisphosphatase 1
P09467 F16P1_HUMAN Homo sapiens Fructose-1,6-bisphosphatase 1
P09467 F16P1_HUMAN Homo sapiens Fructose-1,6-bisphosphatase 1