PDB 2fb8

PDB Information

PDB2FB8
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
King, A.J., Patrick, D.R., Batorsky, R.S., Ho, M.L., Do, H.T., Zhang, S.Y., Kumar, R., Rusnak, D.W., Takle, A.K., Wilson, D.M., Hugger, E., Wang, L., Karreth, F., Lougheed, J.C., Lee, J., Chau, D., Stout, T.J., May, E.W., Rominger, C.M., Schaber, M.D., Luo, L., Lakdawala, A.S., Adams, J.L., Contractor, R.G., Smalley, K.S., Herlyn, M., Morrissey, M.M., Tuveson, D.A., Huang, P.S.
Cancer Res.
HeaderTransferase
Released2005-12-08
Resolution2.900
CATH Insert Date07 Jan, 2007

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2007 Chopped
B 07 Jan, 2007 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2fb8A01 08 Jan, 2007 3.30.200.20 Assigned
2fb8A02 08 Jan, 2007 1.10.510.10 Assigned
2fb8B01 08 Jan, 2007 3.30.200.20 Assigned
2fb8B02 08 Jan, 2007 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf