PDB 2f54

PDB Links
Overview

PDB Information

PDB	2F54
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Dunn, S.M., Rizkallah, P.J., Baston, E., Mahon, T., Cameron, B., Moysey, R., Gao, F., Sami, M., Boulter, J., Li, Y., Jakobsen, B.K. Protein Sci.
Header	Immune System
Released	2005-11-25
Resolution	2.700
CATH Insert Date	14 Jul, 2006

PDB Images (25)

2f54

PDB 2f54

2f54A

PDB Chain 2f54A

2f54B

PDB Chain 2f54B

2f54C

PDB Chain 2f54C

2f54D

PDB Chain 2f54D

2f54E

PDB Chain 2f54E

2f54F

PDB Chain 2f54F

2f54G

PDB Chain 2f54G

2f54H

PDB Chain 2f54H

2f54K

PDB Chain 2f54K

2f54L

PDB Chain 2f54L

2f54A01

CATH Domain 2f54A01

2f54A02

CATH Domain 2f54A02

2f54B00

CATH Domain 2f54B00

2f54D01

CATH Domain 2f54D01

2f54D02

CATH Domain 2f54D02

2f54E01

CATH Domain 2f54E01

2f54E02

CATH Domain 2f54E02

2f54F01

CATH Domain 2f54F01

2f54F02

CATH Domain 2f54F02

2f54G00

CATH Domain 2f54G00

2f54K01

CATH Domain 2f54K01

2f54K02

CATH Domain 2f54K02

2f54L01

CATH Domain 2f54L01

2f54L02

CATH Domain 2f54L02

PDB Prints

PDB Chains (10)

Chain ID	Date inserted into CATH	CATH Status
A	14 Jul, 2006	Chopped
B	14 Jul, 2006	Chopped
C	14 Jul, 2006	Rejected
D	14 Jul, 2006	Chopped
E	14 Jul, 2006	Chopped
F	14 Jul, 2006	Chopped
G	14 Jul, 2006	Chopped
H	14 Jul, 2006	Rejected
K	14 Jul, 2006	Chopped
L	14 Jul, 2006	Chopped

CATH Domains (14)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2f54A01	29 Nov, 2006	3.30.500.10	Assigned
2f54A02	29 Nov, 2006	2.60.40.10	Assigned
2f54B00	16 Oct, 2006	2.60.40.10	Assigned
2f54D01	15 Jul, 2007	2.60.40.10	Assigned
2f54D02	15 Jul, 2007	2.60.40.10	Assigned
2f54E01	15 Jul, 2007	2.60.40.10	Assigned
2f54E02	15 Jul, 2007	2.60.40.10	Assigned
2f54F01	29 Nov, 2006	3.30.500.10	Assigned
2f54F02	29 Nov, 2006	2.60.40.10	Assigned
2f54G00	16 Oct, 2006	2.60.40.10	Assigned
2f54K01	15 Jul, 2007	2.60.40.10	Assigned
2f54K02	15 Jul, 2007	2.60.40.10	Assigned
2f54L01	15 Jul, 2007	2.60.40.10	Assigned
2f54L02	15 Jul, 2007	2.60.40.10	Assigned

UniProtKB Entries (10)

Accession	Gene ID	Taxon	Description
P78358	CTG1B_HUMAN	Homo sapiens	Cancer/testis antigen 1
P01848	TRAC_HUMAN	Homo sapiens	T cell receptor alpha constant
P78358	CTG1B_HUMAN	Homo sapiens	Cancer/testis antigen 1
P01850	TRBC1_HUMAN	Homo sapiens	T cell receptor beta constant 1
P61769	B2MG_HUMAN	Homo sapiens	Beta-2-microglobulin
P01892	1A02_HUMAN	Homo sapiens	HLA class I histocompatibility antigen, A-2 alpha chain
P01892	1A02_HUMAN	Homo sapiens	HLA class I histocompatibility antigen, A-2 alpha chain
P61769	B2MG_HUMAN	Homo sapiens	Beta-2-microglobulin
P01850	TRBC1_HUMAN	Homo sapiens	T cell receptor beta constant 1
P01848	TRAC_HUMAN	Homo sapiens	T cell receptor alpha constant