PDB 2f3e

PDB Links
Overview

PDB Information

PDB	2F3E
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). Hanessian, S., Yang, G., Rondeau, J.-M., Neumann, U., Betschart, C., Tintelnot-Blomley, M. J.Med.Chem.
Header	Hydrolase
Released	2005-11-21
Resolution	2.110
CATH Insert Date	07 Sep, 2006

PDB Images (10)

Image of CATH 2f3e

2f3e

PDB 2f3e

Image of CATH 2f3eA

2f3eA

PDB Chain 2f3eA

Image of CATH 2f3eB

2f3eB

PDB Chain 2f3eB

Image of CATH 2f3eC

2f3eC

PDB Chain 2f3eC

Image of CATH 2f3eA01

2f3eA01

CATH Domain 2f3eA01

Image of CATH 2f3eA02

2f3eA02

CATH Domain 2f3eA02

Image of CATH 2f3eB01

2f3eB01

CATH Domain 2f3eB01

Image of CATH 2f3eB02

2f3eB02

CATH Domain 2f3eB02

Image of CATH 2f3eC01

2f3eC01

CATH Domain 2f3eC01

Image of CATH 2f3eC02

2f3eC02

CATH Domain 2f3eC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	07 Sep, 2006	Chopped
B	07 Sep, 2006	Chopped
C	07 Sep, 2006	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2f3eA01	15 Oct, 2006	2.40.70.10	Assigned
2f3eA02	15 Oct, 2006	2.40.70.10	Assigned
2f3eB01	16 Oct, 2006	2.40.70.10	Assigned
2f3eB02	16 Oct, 2006	2.40.70.10	Assigned
2f3eC01	16 Oct, 2006	2.40.70.10	Assigned
2f3eC02	16 Oct, 2006	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1