PDB 2cw6

PDB Information

PDB2CW6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
Fu, Z., Runquist, J.A., Forouhar, F., Hussain, M., Hunt, J.F., Miziorko, H.M., Kim, J.-J.P.
J.Biol.Chem.
HeaderLyase
Released2005-06-17
Resolution2.100
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
2cw6A00 26 Oct, 2009 3.20.20.70 Assigned
2cw6B00 26 Oct, 2009 3.20.20.70 Assigned
2cw6C00 26 Oct, 2009 3.20.20.70 Assigned
2cw6D00 26 Oct, 2009 3.20.20.70 Assigned
2cw6E00 26 Oct, 2009 3.20.20.70 Assigned
2cw6F00 26 Oct, 2009 3.20.20.70 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial
P35914 HMGCL_HUMAN Homo sapiens Hydroxymethylglutaryl-CoA lyase, mitochondrial