PDB 2bmc

PDB Information

PDB2BMC
MethodX-RAY DIFFRACTION
Host OrganismTRICHOPLUSIA NI
Gene SourceHOMO SAPIENS
Primary Citation
Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
Fancelli, D., Berta, D., Bindi, S., Cameron, A., Cappella, P., Carpinelli, P., Catana, C., Forte, B., Giordano, P., Giorgini, M.L., Mantegani, S., Marsiglio, A., Meroni, M., Moll, J., Pittala, V., Roletto, F., Severino, D., Soncini, C., Storici, P., Tonani, R., Varasi, M., Vulpetti, A., Vianello, P.
J.Med.Chem.
HeaderTransferase
Released2005-03-08
Resolution2.600
CATH Insert Date05 Mar, 2006

PDB Images (19)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2bmcA01 10 Mar, 2006 3.30.200.20 Assigned
2bmcA02 10 Mar, 2006 1.10.510.10 Assigned
2bmcB01 10 Mar, 2006 3.30.200.20 Assigned
2bmcB02 10 Mar, 2006 1.10.510.10 Assigned
2bmcC01 10 Mar, 2006 3.30.200.20 Assigned
2bmcC02 10 Mar, 2006 1.10.510.10 Assigned
2bmcD01 10 Mar, 2006 3.30.200.20 Assigned
2bmcD02 10 Mar, 2006 1.10.510.10 Assigned
2bmcE01 10 Mar, 2006 3.30.200.20 Assigned
2bmcE02 10 Mar, 2006 1.10.510.10 Assigned
2bmcF01 10 Mar, 2006 3.30.200.20 Assigned
2bmcF02 10 Mar, 2006 1.10.510.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A