PDB Information

PDB2AQB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceEscherichia coli
Primary Citation
Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
Kim, P., Zhang, Y.M., Shenoy, G., Nguyen, Q.A., Boshoff, H.I., Manjunatha, U.H., Goodwin, M.B., Lonsdale, J., Price, A.C., Miller, D.J., Duncan, K., White, S.W., Rock, C.O., Barry III, C.E., Dowd, C.S.
J.Med.Chem.
HeaderTransferase
Released2005-08-17
Resolution2.190
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2aqbA01 15 Mar, 2006 3.40.47.10 Assigned
2aqbA02 15 Mar, 2006 3.40.47.10 Assigned
2aqbB01 15 Mar, 2006 3.40.47.10 Assigned
2aqbB02 15 Mar, 2006 3.40.47.10 Assigned
2aqbC01 15 Mar, 2006 3.40.47.10 Assigned
2aqbC02 15 Mar, 2006 3.40.47.10 Assigned
2aqbD01 15 Mar, 2006 3.40.47.10 Assigned
2aqbD02 15 Mar, 2006 3.40.47.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P0A953 FABB_ECOLI Escherichia coli K-12 3-oxoacyl-[acyl-carrier-protein] synthase 1
P0A953 FABB_ECOLI Escherichia coli K-12 3-oxoacyl-[acyl-carrier-protein] synthase 1
P0A953 FABB_ECOLI Escherichia coli K-12 3-oxoacyl-[acyl-carrier-protein] synthase 1
P0A953 FABB_ECOLI Escherichia coli K-12 3-oxoacyl-[acyl-carrier-protein] synthase 1