PDB 2aaz
PDB Information
| PDB | 2AAZ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21 |
| Gene Source | Filobasidiella neoformans |
| Primary Citation | The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition.
Acta Crystallogr.,Sect.D
|
| Header | Transferase |
| Released | 2005-07-14 |
| Resolution | 2.080 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (33)
2aaz
PDB 2aaz
2aazA
PDB Chain 2aazA
2aazB
PDB Chain 2aazB
2aazC
PDB Chain 2aazC
2aazD
PDB Chain 2aazD
2aazE
PDB Chain 2aazE
2aazF
PDB Chain 2aazF
2aazG
PDB Chain 2aazG
2aazH
PDB Chain 2aazH
2aazI
PDB Chain 2aazI
2aazJ
PDB Chain 2aazJ
2aazK
PDB Chain 2aazK
2aazL
PDB Chain 2aazL
2aazM
PDB Chain 2aazM
2aazN
PDB Chain 2aazN
2aazO
PDB Chain 2aazO
2aazP
PDB Chain 2aazP
2aazA00
CATH Domain 2aazA00
2aazB00
CATH Domain 2aazB00
2aazC00
CATH Domain 2aazC00
2aazD00
CATH Domain 2aazD00
2aazE00
CATH Domain 2aazE00
2aazF00
CATH Domain 2aazF00
2aazG00
CATH Domain 2aazG00
2aazH00
CATH Domain 2aazH00
2aazI00
CATH Domain 2aazI00
2aazJ00
CATH Domain 2aazJ00
2aazK00
CATH Domain 2aazK00
2aazL00
CATH Domain 2aazL00
2aazM00
CATH Domain 2aazM00
2aazN00
CATH Domain 2aazN00
2aazO00
CATH Domain 2aazO00
2aazP00
CATH Domain 2aazP00
PDB Prints
PDB Chains (16)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
| C | 05 Mar, 2006 | Chopped |
| D | 05 Mar, 2006 | Chopped |
| E | 05 Mar, 2006 | Chopped |
| F | 05 Mar, 2006 | Chopped |
| G | 05 Mar, 2006 | Chopped |
| H | 05 Mar, 2006 | Chopped |
| I | 05 Mar, 2006 | Chopped |
| J | 05 Mar, 2006 | Chopped |
| K | 05 Mar, 2006 | Chopped |
| L | 05 Mar, 2006 | Chopped |
| M | 05 Mar, 2006 | Chopped |
| N | 05 Mar, 2006 | Chopped |
| O | 05 Mar, 2006 | Chopped |
| P | 05 Mar, 2006 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2aazA00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazB00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazC00 | 01 Dec, 2006 | 3.30.572.10 | Assigned |
| 2aazD00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazE00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazF00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazG00 | 28 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazH00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazI00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazJ00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazK00 | 28 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazL00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazM00 | 30 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazN00 | 17 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazO00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
| 2aazP00 | 29 Nov, 2006 | 3.30.572.10 | Assigned |
UniProtKB Entries (16)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |
| P0CS12 | TYSY_CRYNJ | Cryptococcus neoformans var. neoformans JEC21 | Thymidylate synthase |