PDB Information

PDB2A4R
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Hepatitis C Virus NS3-4A serine protease inhibitors: Use of a P2-P1 cyclopropyl alanine combination for improved potency.
Bogen, S., Saksena, A.K., Arasappan, A., Gu, H., Njoroge, F.G., Girijavallabhan, V., Pichardo, J., Butkiewicz, N., Prongay, A., Madison, V.
Bioorg.Med.Chem.Lett.
HeaderViral Protein
Released2005-06-29
Resolution2.400
CATH Insert Date14 Jul, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Rejected
C 14 Jul, 2006 Chopped
D 14 Jul, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2a4rA01 16 Oct, 2006 2.40.10.120 Assigned
2a4rA02 16 Oct, 2006 2.40.10.10 Assigned
2a4rC01 16 Oct, 2006 2.40.10.120 Assigned
2a4rC02 16 Oct, 2006 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein