PDB Information

PDB1Z6J
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa.
Schweitzer, B.A., Neumann, W.L., Rahman, H.K., Kusturin, C.L., Sample, K.R., Poda, G.I., Kurumbail, R.G., Stevens, A.M., Stegeman, R.A., Stallings, W.C., South, M.S.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2005-03-22
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped
T 05 Mar, 2006 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
1z6jH01 21 Oct, 2006 2.40.10.10 Assigned
1z6jH02 21 Oct, 2006 2.40.10.10 Assigned
1z6jL01 29 Aug, 2007 Holding pen
1z6jT01 10 Mar, 2006 2.60.40.10 Assigned
1z6jT02 10 Mar, 2006 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P13726 TF_HUMAN Homo sapiens Tissue factor
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
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