PDB 1z3n

PDB Information

PDB1Z3N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Van Zandt, M.C., Jones, M.L., Gunn, D.E., Geraci, L.S., Jones, J.H., Sawicki, D.R., Sredy, J., Jacot, J.L., Dicioccio, A.T., Petrova, T., Mitschler, A., Podjarny, A.D.
J.Med.Chem.
HeaderOxidoreductase
Released2005-03-14
Resolution1.040
CATH Insert Date17 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1z3nA00 18 Mar, 2006 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1