PDB Information

PDB1YW7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
Sheppard, G.S., Wang, J., Kawai, M., Fidanze, S.D., BaMaung, N.Y., Erickson, S.A., Barnes, D.M., Tedrow, J.S., Kolaczkowski, L., Vasudevan, A., Park, D.C., Wang, G.T., Sanders, W.J., Mantei, R.A., Palazzo, F., Tucker-Garcia, L., Lou, P., Zhang, Q., Park, C.H., Kim, K.H., Petros, A., Olejniczak, E., Nettesheim, D., Hajduk, P., Henkin, J., Lesniewski, R., Davidsen, S.K., Bell, R.L.
J.Med.Chem.
HeaderHydrolase
Released2005-02-17
Resolution1.850
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1yw7A01 17 Mar, 2006 3.90.230.10 Assigned
1yw7A02 17 Mar, 2006 1.10.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P50579 MAP2_HUMAN Homo sapiens Methionine aminopeptidase 2
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