PDB Information

PDB1Y2E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design
Card, G.L., Blasdel, L., England, B.P., Zhang, C., Suzuki, Y., Gillette, S., Fong, D., Ibrahim, P.N., Artis, D.R., Bollag, G., Milburn, M.V., Kim, S.-H., Schlessinger, J., Zhang, K.Y.J.
Nat.Biotechnol.
HeaderHydrolase
Released2004-11-22
Resolution2.100
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1y2eA00 09 Mar, 2006 1.10.1300.10 Assigned
1y2eB00 09 Mar, 2006 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D