PDB 1xn2
PDB Information
| PDB | 1XN2 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21 |
| Gene Source | Homo sapiens |
| Primary Citation | Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Biochemistry
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2004-10-04 |
| Resolution | 1.900 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (17)
1xn2
PDB 1xn2
1xn2A
PDB Chain 1xn2A
1xn2B
PDB Chain 1xn2B
1xn2C
PDB Chain 1xn2C
1xn2D
PDB Chain 1xn2D
1xn2E
PDB Chain 1xn2E
1xn2F
PDB Chain 1xn2F
1xn2G
PDB Chain 1xn2G
1xn2H
PDB Chain 1xn2H
1xn2A01
CATH Domain 1xn2A01
1xn2A02
CATH Domain 1xn2A02
1xn2B01
CATH Domain 1xn2B01
1xn2B02
CATH Domain 1xn2B02
1xn2C01
CATH Domain 1xn2C01
1xn2C02
CATH Domain 1xn2C02
1xn2D01
CATH Domain 1xn2D01
1xn2D02
CATH Domain 1xn2D02
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
| C | 05 Mar, 2006 | Chopped |
| D | 05 Mar, 2006 | Chopped |
| E | 05 Mar, 2006 | Rejected |
| F | 05 Mar, 2006 | Rejected |
| G | 05 Mar, 2006 | Rejected |
| H | 05 Mar, 2006 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 1xn2A01 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2A02 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2B01 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2B02 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2C01 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2C02 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2D01 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
| 1xn2D02 | 09 Mar, 2006 | 2.40.70.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |