PDB Information

PDB1TWX
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Crystal structure of the thrombin mutant D221A/D222K: the Asp222:Arg187 ion-pair stabilizes the fast form
Pineda, A.O., Zhang, E., Guinto, E.R., Savvides, S.N., Tulinsky, A., Di Cera, E.
Biophys.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2004-07-01
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Rejected
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1twxB01 16 Oct, 2006 2.40.10.10 Assigned
1twxB02 16 Oct, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P28504 HIR2_HIRME Hirudo medicinalis Hirudin-2
P00734 THRB_HUMAN Homo sapiens Prothrombin