PDB 1tw6

PDB Links
Overview

PDB Information

PDB	1TW6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP Vucic, D., Franklin, M.C., Wallweber, H.J.A., Das, K., Eckelman, B.P., Shin, H., Elliott, L.O., Kadkhodayan, S., Deshayes, K., Salvesen, G.S., Fairbrother, W.J. Biochem.J.
Header	Inhibitor/Apoptosis
Released	2004-06-30
Resolution	1.710
CATH Insert Date	05 Mar, 2006

PDB Images (7)

Image of CATH 1tw6

1tw6

PDB 1tw6

Image of CATH 1tw6A

1tw6A

PDB Chain 1tw6A

Image of CATH 1tw6B

1tw6B

PDB Chain 1tw6B

Image of CATH 1tw6C

1tw6C

PDB Chain 1tw6C

Image of CATH 1tw6D

1tw6D

PDB Chain 1tw6D

Image of CATH 1tw6A00

1tw6A00

CATH Domain 1tw6A00

Image of CATH 1tw6B00

1tw6B00

CATH Domain 1tw6B00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped
C	05 Mar, 2006	Rejected
D	05 Mar, 2006	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1tw6A00	05 Mar, 2006	1.10.1170.10	Assigned
1tw6B00	05 Mar, 2006	1.10.1170.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q96CA5	BIRC7_HUMAN	Homo sapiens	Baculoviral IAP repeat-containing protein 7
Q96CA5	BIRC7_HUMAN	Homo sapiens	Baculoviral IAP repeat-containing protein 7
Q9NR28	DBLOH_HUMAN	Homo sapiens	Diablo homolog, mitochondrial
Q9NR28	DBLOH_HUMAN	Homo sapiens	Diablo homolog, mitochondrial