PDB Information

PDB1T3R
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor
Surleraux, D.L., Tahri, A., Verschueren, W.G., Pille, G.M., de Kock, H.A., Jonckers, T.H., Peeters, A., De Meyer, S., Azijn, H., Pauwels, R., de Bethune, M.P., King, N.M., Prabu-Jeyabalan, M., Schiffer, C.A., Wigerinck, P.B.
J.Med.Chem.
HeaderHydrolase
Released2004-04-27
Resolution1.200
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1t3rA00 09 Mar, 2006 2.40.70.10 Assigned
1t3rB00 09 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03369 POL_HV1A2 HIV-1 M:B_ARV2/SF2 Gag-Pol polyprotein
P03369 POL_HV1A2 HIV-1 M:B_ARV2/SF2 Gag-Pol polyprotein