PDB Information

PDB1S9I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
Ohren, J.F., Chen, H., Pavlovsky, A., Whitehead, C., Zhang, E., Kuffa, P., Yan, C., McConnell, P., Spessard, C., Banotai, C., Mueller, W.T., Delaney, A., Omer, C., Sebolt-Leopold, J., Dudley, D.T., Leung, I.K., Flamme, C., Warmus, J., Kaufman, M., Barrett, S., Tecle, H., Hasemann, C.A.
Nat.Struct.Mol.Biol.
HeaderTransferase
Released2004-02-04
Resolution3.200
CATH Insert Date05 Mar, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1s9iA01 05 Mar, 2006 3.30.200.20 Assigned
1s9iA02 05 Mar, 2006 1.10.510.10 Assigned
1s9iB01 05 Mar, 2006 3.30.200.20 Assigned
1s9iB02 05 Mar, 2006 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P36507 MP2K2_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2
P36507 MP2K2_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2