PDB Information

PDB1Q0Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceEscherichia coli
Primary Citation
The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
Mac Sweeney, A., Lange, R., Fernandes, R.P., Schulz, H., Dale, G.E., Douangamath, A., Proteau, P.J., Oefner, C.
J.Mol.Biol.
HeaderOxidoreductase
Released2003-07-17
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
1q0qA01 31 Aug, 2007 3.40.50.720 Assigned
1q0qA02 31 Aug, 2007 Holding pen
1q0qA03 31 Aug, 2007 1.10.1740.10 Assigned
1q0qB01 31 Aug, 2007 3.40.50.720 Assigned
1q0qB02 31 Aug, 2007 Holding pen
1q0qB03 31 Aug, 2007 1.10.1740.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45568 DXR_ECOLI Escherichia coli K-12 1-deoxy-D-xylulose 5-phosphate reductoisomerase
P45568 DXR_ECOLI Escherichia coli K-12 1-deoxy-D-xylulose 5-phosphate reductoisomerase
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