PDB Information

PDB1NI1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceRattus norvegicus
Primary Citation
Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Tong, Y., Lin, N.H., Wang, L., Hasvold, L., Wang, W., Leonard, N., Li, T., Li, Q., Cohen, J., Gu, W.Z., Zhang, H., Stoll, V., Bauch, J., Marsh, K., Rosenberg, S.H., Sham, H.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2002-12-20
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1ni1A00 05 Mar, 2006 1.25.40.120 Assigned
1ni1B00 05 Mar, 2006 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02293 FNTB_RAT Rattus norvegicus Protein farnesyltransferase subunit beta
Q04631 FNTA_RAT Rattus norvegicus Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
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