PDB Information

PDB1MHW
MethodX-RAY DIFFRACTION
Host OrganismPichia pastoris
Gene SourceHomo sapiens
Primary Citation
Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
Chowdhury, S., Sivaraman, J., Wang, J., Devanathan, G., Lachance, P., Qi, H., Menard, R., Lefebvre, J., Konishi, Y., Cygler, M., Sulea, T., Purisima, E.O.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2002-08-21
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Rejected
F 05 Mar, 2006 Rejected
G 05 Mar, 2006 Rejected
H 05 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1mhwA00 05 Mar, 2006 3.90.70.10 Assigned
1mhwB00 05 Mar, 2006 3.90.70.10 Assigned
1mhwC00 05 Mar, 2006 2.40.50.170 Assigned
1mhwD00 05 Mar, 2006 2.40.50.170 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1