PDB Information

PDB1LYB
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceStreptomyces argenteolus subsp. toyonakensis
Primary Citation
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Baldwin, E.T., Bhat, T.N., Gulnik, S., Hosur, M.V., Sowder 2nd., R.C., Cachau, R.E., Collins, J., Silva, A.M., Erickson, J.W.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase/Hydrolase Inhibitor
Released1993-04-22
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
J 05 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1lybA00 05 Mar, 2006 2.40.70.10 Assigned
1lybB00 05 Mar, 2006 2.40.70.10 Assigned
1lybC00 05 Mar, 2006 2.40.70.10 Assigned
1lybD00 05 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P07339 CATD_HUMAN Homo sapiens Cathepsin D
P07339 CATD_HUMAN Homo sapiens Cathepsin D
P07339 CATD_HUMAN Homo sapiens Cathepsin D
P07339 CATD_HUMAN Homo sapiens Cathepsin D