PDB Information

PDB1HPS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'--P2' amide bond isostere.
Thompson, S.K., Murthy, K.H., Zhao, B., Winborne, E., Green, D.W., Fisher, S.M., DesJarlais, R.L., Tomaszek Jr., T.A., Meek, T.D., Gleason, J.G., Abdel-Meguid, S.S.
J.Med.Chem.
HeaderHydrolase(Acid Proteinase)
Released1994-05-24
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1hpsA00 05 Mar, 2006 2.40.70.10 Assigned
1hpsB00 05 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
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