PDB Information

PDB1FBZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.
Shakespeare, W., Yang, M., Bohacek, R., Cerasoli, F., Stebbins, K., Sundaramoorthi, R., Azimioara, M., Vu, C., Pradeepan, S., Metcalf, C., Haraldson, C., Merry, T., Dalgarno, D., Narula, S., Hatada, M., Lu, X., van Schravendijk, M.R., Adams, S., Violette, S., Smith, J., Guan, W., Bartlett, C., Herson, J., Iuliucci, J., Weigele, M., Sawyer, T.
Proc.Natl.Acad.Sci.Usa
HeaderTransferase
Released2000-07-17
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1fbzA00 05 Mar, 2006 3.30.505.10 Assigned
1fbzB00 05 Mar, 2006 3.30.505.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P06239 LCK_HUMAN Homo sapiens Tyrosine-protein kinase Lck
P06239 LCK_HUMAN Homo sapiens Tyrosine-protein kinase Lck
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