PDB Information

PDB1C6Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Munshi, S., Chen, Z., Yan, Y., Li, Y., Olsen, D.B., Schock, H.B., Galvin, B.B., Dorsey, B., Kuo, L.C.
Acta Crystallogr.,Sect.D
HeaderHydrolase/Hydrolase Inhibitor
Released1999-12-28
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1c6zA00 05 Mar, 2006 2.40.70.10 Assigned
1c6zB00 05 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O09893 O09893_9HIV1 Human immunodeficiency virus 1 Protease
O09893 O09893_9HIV1 Human immunodeficiency virus 1 Protease