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CATH Superfamily 3.40.50.12580

CDP-glycerol glycerophosphotransferase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: CDP-glycerol glycerophosphotransferase, C-terminal domain

Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of Gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase TagF is responsible for the polymerisation of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid PMID:10648531. The TagF-like family of enzymes has been shown to be responsible for wall teichoic acid priming and polymerization events PMID:19520862,PMID:21035733. This entry represents the C-terminal domain of TagF which exhibits a Rossmann-fold.

PMID:10648531 PMID:19520862 PMID:21035733(INTERPRO:IPR007554)

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
6 Unique EC terms

Species Diversity

Unique species annotations
4980 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 20
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 5
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 2
Function
Unique EC: 6
Unique GO: 1
Taxonomy
Unique Species: 4980