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CATH Superfamily 3.40.50.11000

Fe-S cluster assembly protein Dre2, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fe-S cluster assembly protein Dre2, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Fe-S cluster assembly protein Dre2, N-terminal domain

Structural domains comprising this superfamily share the structure of the N-terminal domain of the yeast protein Dre2, an essential Fe-S cluster-containing protein that has been implicated in cytosolic Fe-S protein biogenesis and in cell death regulation in response to oxidative stress. It function is however not yet fully understood. Structural studies of this N-terminal domain have shown it consists of a stable well-structured monomer with an overall typical S-adenosylmethionine methyltransferase fold, even when lacking two alpha-helices and one beta-sheet PMID:22487307

GO Diversity

Unique GO annotations
10 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
408 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 6
Function
Unique EC:
Unique GO: 10
Taxonomy
Unique Species: 408