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CATH Superfamily 1.25.40.70

Phosphatidylinositol 3-kinase, accessory domain (PIK)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase, accessory domain (PIK)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Phosphatidylinositol 3-kinase, accessory domain (PIK)

Phosphatidylinositol 3-kinase (PI3-kinase) (EC:2.7.1.137) is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. The role of the accessory domain of phosphoinositide 3-kinase (PI3-kinase) is unclear. It may be involved in substrate presentation PMID:8248783.

GO Diversity

Unique GO annotations
354 Unique GO terms

EC Diversity

Unique EC annotations
5 Unique EC terms

Species Diversity

Unique species annotations
1727 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 177
Domain clusters (>95% seq id): 12
Domain clusters (>35% seq id): 7
Unique PDBs: 162
Alignments
Structural Clusters (5A): 2
Structural Clusters (9A): 2
FunFam Clusters: 90
Function
Unique EC: 5
Unique GO: 354
Taxonomy
Unique Species: 1727
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