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CATH Superfamily 1.20.58.1470

FTO C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
FTO C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: FTO C-terminal domain

This superfamily is made up of 4 alpha helices in a bundle.

One end of the helix bundle interacts with the N-terminal domain of FTO, and it has been suggested that the CTD plays a role in stabilising the NTD's conformation since the NTD only exhibits enzymatic activity when co-expressed with the CTD.

GO Diversity

Unique GO annotations
28 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
171 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 21
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 18
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC: 1
Unique GO: 28
Taxonomy
Unique Species: 171
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