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Practical

Introduction

The presentation is available here:

eccb2012_t2_romainstuder.pdf.zip

Useful tools

Jalview: http://www.jalview.org/download.html (It could be better to increase the memory allocated to java: http://www.jalview.org/jvmmemoryparams.html )

PyMOL: http://sourceforge.net/projects/pymol/ (or http://sourceforge.net/projects/pymol/files/Legacy/)

NJplot: http://pbil.univ-lyon1.fr/software/njplot.html

Part I on amino acids dataset:

  • BADASP: Analysis of the V-type proton ATPase 116 kDa subunit a gene family (Linux / MacOSX / Windows)
  • TDG09: Analysis of the Hemagglutinin HA1 chain (Linux / MacOSX / Windows)
  • FunDi: Analysis of the GAPDH (Linux / MacOSX)
  • Diverge 2: Analysis of the GAPDH (Windows)

Part II on nucleotides dataset:

  • Codeml / PAML: Detection of positive selection in the serine/threonine-protein kinase gene family (Linux / MacOSX / Windows)

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CATH: Protein Structure Classification Database by I. Sillitoe, N. Dawson, T. Lewis, D. Lee, J. Lees, C. Orengo is licensed under a Creative Commons Attribution 4.0 International License.
Based on work at https://cath.biochem.ucl.ac.uk.