CATH Superfamily 6.10.140.2200

FunFam 1: Cbp/p300-interacting transactivator 2 isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	7	O35740 (/IDA) Q99967 (/IDA) Q99967 (/IDA) Q9I8K7 (/IDA) Q9I8K7 (/IDA) Q9WUL8 (/IDA) Q9WUL8 (/IDA)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	6	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS) Q99MA1 (/ISS) Q9WUL8 (/ISS) Q9WUL8 (/ISS)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	5	Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	4	A1YFU7 (/ISS) Q0VCT9 (/ISS) Q99967 (/ISS) Q99967 (/ISS)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	3	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS)
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	3	O35740 (/IPI) Q99967 (/IPI) Q99967 (/IPI)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	2	Q9WUL8 (/IPI) Q9WUL8 (/IPI)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	2	Q99967 (/IDA) Q99967 (/IDA)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	2	Q99967 (/IMP) Q99967 (/IMP)
Protein domain specific binding GO:0019904 Interacting selectively and non-covalently with a specific domain of a protein.	2	Q99967 (/IPI) Q99967 (/IPI)
Histone acetyltransferase binding GO:0035035 Interacting selectively and non-covalently with the enzyme histone acetyltransferase.	2	Q99967 (/IDA) Q99967 (/IDA)
LBD domain binding GO:0050693 Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.	2	Q99967 (/IPI) Q99967 (/IPI)
RNA polymerase II activating transcription factor binding GO:0001102 Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.	1	O35740 (/IPI)
RNA polymerase II activating transcription factor binding GO:0001102 Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.	1	Q9DDW4 (/ISA)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	1	O35740 (/IDA)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	1	Q9DDW4 (/ISA)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	1	O35740 (/IDA)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	1	Q9DDW4 (/ISA)
Transcription coregulator activity GO:0003712 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.	1	O35740 (/TAS)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	1	Q9DDW4 (/ISA)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	1	O35740 (/ISO)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	1	O35740 (/ISO)
Protein domain specific binding GO:0019904 Interacting selectively and non-covalently with a specific domain of a protein.	1	O35740 (/ISO)
Histone acetyltransferase binding GO:0035035 Interacting selectively and non-covalently with the enzyme histone acetyltransferase.	1	O35740 (/ISO)
SMAD binding GO:0046332 Interacting selectively and non-covalently with a SMAD signaling protein.	1	O35740 (/IPI)
SMAD binding GO:0046332 Interacting selectively and non-covalently with a SMAD signaling protein.	1	Q9DDW4 (/ISA)
LBD domain binding GO:0050693 Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.	1	O35740 (/ISO)

There are 165 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	8	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS) Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	6	O35740 (/ISS) Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Response to estrogen GO:0043627 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	6	Q99967 (/IDA) Q99967 (/IDA) Q9I8K7 (/IDA) Q9I8K7 (/IDA) Q9WUL8 (/IDA) Q9WUL8 (/IDA)
Determination of left/right symmetry GO:0007368 The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	5	Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.	5	Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Positive regulation of cell cycle GO:0045787 Any process that activates or increases the rate or extent of progression through the cell cycle.	5	Q6NX30 (/ISS) Q99967 (/ISS) Q99967 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	5	O35740 (/IDA) Q99967 (/IDA) Q99967 (/IDA) Q9WUL8 (/IDA) Q9WUL8 (/IDA)
Regulation of animal organ formation GO:0003156 Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.	4	A1YFU7 (/ISS) Q0VCT9 (/ISS) Q99967 (/ISS) Q99967 (/ISS)
Sex determination GO:0007530 Any process that establishes and transmits the specification of sexual status of an individual organism.	4	A1YFU7 (/ISS) Q0VCT9 (/ISS) Q99967 (/ISS) Q99967 (/ISS)
Adrenal cortex formation GO:0035802 The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).	4	A1YFU7 (/ISS) Q0VCT9 (/ISS) Q99967 (/ISS) Q99967 (/ISS)
Positive regulation of male gonad development GO:2000020 Any process that activates or increases the frequency, rate or extent of male gonad development.	4	A1YFU7 (/ISS) Q0VCT9 (/ISS) Q99967 (/ISS) Q99967 (/ISS)
Response to hypoxia GO:0001666 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	3	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	3	O35740 (/IMP) Q99967 (/IMP) Q99967 (/IMP)
Positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	3	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS)
Muscle cell differentiation GO:0042692 The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.	3	A8E5L7 (/IMP) B7ZVN5 (/IMP) Q90ZR5 (/IMP)
Response to estrogen GO:0043627 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	3	A1YFU7 (/ISS) O35740 (/ISS) Q0VCT9 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	Q99967 (/IMP) Q99967 (/IMP)
Response to hypoxia GO:0001666 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	2	Q99967 (/IDA) Q99967 (/IDA)
Response to hypoxia GO:0001666 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	2	Q99967 (/IMP) Q99967 (/IMP)
Liver development GO:0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.	2	Q99967 (/ISS) Q99967 (/ISS)
Outflow tract morphogenesis GO:0003151 The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.	2	Q99967 (/ISS) Q99967 (/ISS)
Cell population proliferation GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population.	2	Q99967 (/IDA) Q99967 (/IDA)
Cell population proliferation GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population.	2	O35740 (/ISS) Q99MA1 (/ISS)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	Q99967 (/IDA) Q99967 (/IDA)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	O35740 (/ISS) Q99MA1 (/ISS)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	Q99967 (/IDA) Q99967 (/IDA)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	O35740 (/ISS) Q99MA1 (/ISS)
Positive regulation of cell-cell adhesion GO:0022409 Any process that activates or increases the rate or extent of cell adhesion to another cell.	2	Q99967 (/ISS) Q99967 (/ISS)
Negative regulation of cell migration GO:0030336 Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.	2	Q99967 (/IMP) Q99967 (/IMP)
Response to fluid shear stress GO:0034405 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	2	Q99967 (/IMP) Q99967 (/IMP)
Positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	2	Q99967 (/IDA) Q99967 (/IDA)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	2	Q99967 (/ISS) Q99967 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	2	Q99967 (/IDA) Q99967 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	2	Q99967 (/IMP) Q99967 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	2	O35740 (/ISS) Q99MA1 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	2	Q99967 (/IDA) Q99967 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	2	Q99967 (/ISS) Q99967 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	2	Q99967 (/TAS) Q99967 (/TAS)
Spleen development GO:0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	2	Q99967 (/ISS) Q99967 (/ISS)
Ventricular septum morphogenesis GO:0060412 The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.	2	Q99967 (/ISS) Q99967 (/ISS)
Embryonic heart tube left/right pattern formation GO:0060971 The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.	2	Q99967 (/ISS) Q99967 (/ISS)
Negative regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061428 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	2	Q99967 (/IDA) Q99967 (/IDA)
Left/right axis specification GO:0070986 The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).	2	Q99967 (/ISS) Q99967 (/ISS)
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164 A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.	2	Q99967 (/ISS) Q99967 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	O35740 (/ISO)
Blood vessel development GO:0001568 The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.	1	O35740 (/IMP)
Blood vessel development GO:0001568 The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.	1	Q9DDW4 (/ISA)
Vasculogenesis GO:0001570 The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.	1	O35740 (/IMP)
Vasculogenesis GO:0001570 The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.	1	Q9DDW4 (/ISA)
Response to hypoxia GO:0001666 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	1	O35740 (/ISO)
In utero embryonic development GO:0001701 The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.	1	O35740 (/IMP)
Trophectodermal cell differentiation GO:0001829 The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.	1	O35740 (/IMP)
Neural tube formation GO:0001841 The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.	1	O35740 (/IMP)
Neural tube formation GO:0001841 The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.	1	Q9DDW4 (/ISA)
Neural tube closure GO:0001843 The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.	1	O35740 (/IMP)
Neural tube closure GO:0001843 The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.	1	Q9DDW4 (/ISA)
Liver development GO:0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.	1	O35740 (/IMP)
Liver development GO:0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.	1	Q9DDW4 (/ISA)
Embryonic placenta development GO:0001892 The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	1	O35740 (/IMP)
Vasculature development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	1	O35740 (/IGI)
Vasculature development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	1	O35740 (/IMP)
Vasculature development GO:0001944 The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	1	Q9DDW4 (/ISA)
Heart looping GO:0001947 The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	1	O35740 (/IMP)
Heart looping GO:0001947 The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	1	Q9DDW4 (/ISA)
Lens morphogenesis in camera-type eye GO:0002089 The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	1	O35740 (/IMP)
Lens morphogenesis in camera-type eye GO:0002089 The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	1	Q9DDW4 (/ISA)
Hematopoietic progenitor cell differentiation GO:0002244 The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.	1	O35740 (/IMP)
Hematopoietic progenitor cell differentiation GO:0002244 The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.	1	Q9DDW4 (/ISA)
Leukocyte differentiation GO:0002521 The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	1	O35740 (/IMP)
Leukocyte differentiation GO:0002521 The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	1	Q9DDW4 (/ISA)
Outflow tract morphogenesis GO:0003151 The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.	1	O35740 (/IMP)
Outflow tract morphogenesis GO:0003151 The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.	1	Q9DDW4 (/ISA)
Regulation of animal organ formation GO:0003156 Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.	1	O35740 (/IMP)
Regulation of animal organ formation GO:0003156 Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.	1	Q9DDW4 (/ISA)
Endocardial cushion development GO:0003197 The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	1	O35740 (/IMP)
Endocardial cushion development GO:0003197 The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	1	Q9DDW4 (/ISA)
Ventricular septum development GO:0003281 The progression of the ventricular septum over time from its formation to the mature structure.	1	O35740 (/IMP)
Ventricular septum development GO:0003281 The progression of the ventricular septum over time from its formation to the mature structure.	1	Q9DDW4 (/ISA)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	1	O35740 (/TAS)
Regulation of transcription by RNA polymerase II GO:0006357 Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	O35740 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357 Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	Q9DDW4 (/ISA)
Transforming growth factor beta receptor signaling pathway GO:0007179 A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	1	O35740 (/IDA)
Transforming growth factor beta receptor signaling pathway GO:0007179 A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	1	Q9DDW4 (/ISA)
Determination of left/right symmetry GO:0007368 The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	1	O35740 (/IMP)
Determination of left/right symmetry GO:0007368 The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	1	Q9DDW4 (/ISA)
Central nervous system development GO:0007417 The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	1	O35740 (/IMP)
Central nervous system development GO:0007417 The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	1	Q9DDW4 (/ISA)
Peripheral nervous system development GO:0007422 The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.	1	O35740 (/IMP)
Peripheral nervous system development GO:0007422 The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.	1	Q9DDW4 (/ISA)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	1	Q9DDW4 (/ISA)
Heart development GO:0007507 The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	1	O35740 (/ISO)
Sex determination GO:0007530 Any process that establishes and transmits the specification of sexual status of an individual organism.	1	O35740 (/IMP)
Sex determination GO:0007530 Any process that establishes and transmits the specification of sexual status of an individual organism.	1	Q9DDW4 (/ISA)
Cell aging GO:0007569 An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).	1	Q99MA1 (/IEP)
Cell population proliferation GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population.	1	O35740 (/ISO)
Male gonad development GO:0008584 The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.	1	O35740 (/IGI)
Male gonad development GO:0008584 The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.	1	Q9DDW4 (/ISA)
Response to mechanical stimulus GO:0009612 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	1	Q99MA1 (/IEP)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	Q99MA1 (/IMP)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	O35740 (/ISO)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	Q99MA1 (/IMP)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	O35740 (/ISO)
Cranial nerve morphogenesis GO:0021602 The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	1	O35740 (/IMP)
Cranial nerve morphogenesis GO:0021602 The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	1	Q9DDW4 (/ISA)
Positive regulation of cell-cell adhesion GO:0022409 Any process that activates or increases the rate or extent of cell adhesion to another cell.	1	O35740 (/IMP)
Positive regulation of cell-cell adhesion GO:0022409 Any process that activates or increases the rate or extent of cell adhesion to another cell.	1	Q9DDW4 (/ISA)
Adrenal gland development GO:0030325 The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.	1	O35740 (/IMP)
Adrenal gland development GO:0030325 The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.	1	Q9DDW4 (/ISA)
Negative regulation of cell migration GO:0030336 Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.	1	O35740 (/ISO)
Positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.	1	O35740 (/IDA)
Positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.	1	Q9DDW4 (/ISA)
Granulocyte differentiation GO:0030851 The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.	1	O35740 (/IMP)
Granulocyte differentiation GO:0030851 The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.	1	Q9DDW4 (/ISA)
Response to fluid shear stress GO:0034405 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	1	O35740 (/ISO)
Positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	1	O35740 (/ISO)
Adrenal cortex formation GO:0035802 The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).	1	O35740 (/IMP)
Adrenal cortex formation GO:0035802 The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).	1	Q9DDW4 (/ISA)
Skeletal muscle cell differentiation GO:0035914 The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.	1	O35740 (/IMP)
Skeletal muscle cell differentiation GO:0035914 The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.	1	Q9DDW4 (/ISA)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	O35740 (/IMP)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	Q9DDW4 (/ISA)
Response to estrogen GO:0043627 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	1	O35740 (/ISO)
Positive regulation of cell cycle GO:0045787 Any process that activates or increases the rate or extent of progression through the cell cycle.	1	O35740 (/IMP)
Positive regulation of cell cycle GO:0045787 Any process that activates or increases the rate or extent of progression through the cell cycle.	1	Q9DDW4 (/ISA)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	1	O35740 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	1	Q9DDW4 (/ISA)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	1	O35740 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	O35740 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	Q9DDW4 (/ISA)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	O35740 (/ISO)
Decidualization GO:0046697 The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.	1	O35740 (/IMP)
Spleen development GO:0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	1	O35740 (/IMP)
Spleen development GO:0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	1	Q9DDW4 (/ISA)
Thymus development GO:0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	1	O35740 (/IGI)
Thymus development GO:0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	1	O35740 (/IMP)
Thymus development GO:0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	1	Q9DDW4 (/ISA)
Embryonic camera-type eye morphogenesis GO:0048596 The process in which the anatomical structures of the eye are generated and organized during embryonic development.	1	O35740 (/IGI)
Embryonic camera-type eye morphogenesis GO:0048596 The process in which the anatomical structures of the eye are generated and organized during embryonic development.	1	Q9DDW4 (/ISA)
Erythrocyte development GO:0048821 The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.	1	O35740 (/IMP)
Erythrocyte development GO:0048821 The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.	1	Q9DDW4 (/ISA)
Negative regulation of cardiac muscle cell proliferation GO:0060044 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.	1	Q99MA1 (/IMP)
Negative regulation of cardiac muscle cell proliferation GO:0060044 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.	1	O35740 (/ISO)
Embryonic process involved in female pregnancy GO:0060136 A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.	1	O35740 (/IMP)
Bone morphogenesis GO:0060349 The process in which bones are generated and organized.	1	O35740 (/IMP)
Bone morphogenesis GO:0060349 The process in which bones are generated and organized.	1	Q9DDW4 (/ISA)
Cardiac septum morphogenesis GO:0060411 The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	1	O35740 (/IMP)
Cardiac septum morphogenesis GO:0060411 The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	1	Q9DDW4 (/ISA)
Ventricular septum morphogenesis GO:0060412 The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.	1	O35740 (/IMP)
Ventricular septum morphogenesis GO:0060412 The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.	1	Q9DDW4 (/ISA)
Embryonic heart tube left/right pattern formation GO:0060971 The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.	1	O35740 (/IMP)
Embryonic heart tube left/right pattern formation GO:0060971 The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.	1	Q9DDW4 (/ISA)
Pulmonary artery morphogenesis GO:0061156 The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.	1	O35740 (/IMP)
Pulmonary artery morphogenesis GO:0061156 The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.	1	Q9DDW4 (/ISA)
Cardiac neural crest cell development involved in heart development GO:0061308 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.	1	O35740 (/IMP)
Cardiac neural crest cell development involved in heart development GO:0061308 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.	1	Q9DDW4 (/ISA)
Determination of heart left/right asymmetry GO:0061371 Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.	1	O35740 (/IMP)
Determination of heart left/right asymmetry GO:0061371 Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.	1	Q9DDW4 (/ISA)
Negative regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061428 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	1	O35740 (/ISO)
Left/right axis specification GO:0070986 The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).	1	O35740 (/IMP)
Left/right axis specification GO:0070986 The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).	1	Q9DDW4 (/ISA)
Cellular response to growth factor stimulus GO:0071363 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	1	Q99MA1 (/IEP)
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164 A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.	1	O35740 (/IMP)
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164 A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.	1	Q9DDW4 (/ISA)
Positive regulation of male gonad development GO:2000020 Any process that activates or increases the frequency, rate or extent of male gonad development.	1	O35740 (/IMP)
Positive regulation of male gonad development GO:2000020 Any process that activates or increases the frequency, rate or extent of male gonad development.	1	Q9DDW4 (/ISA)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	5	O35740 (/IDA) Q99967 (/IDA) Q99967 (/IDA) Q9WUL8 (/IDA) Q9WUL8 (/IDA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	3	Q6NX30 (/ISS) Q99MA1 (/ISS) Q9DDW4 (/ISS)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	2	Q99967 (/ISS) Q99967 (/ISS)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	2	Q99967 (/TAS) Q99967 (/TAS)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	2	Q9WUL8 (/IDA) Q9WUL8 (/IDA)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	2	Q99967 (/IMP) Q99967 (/IMP)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	1	O35740 (/IDA)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	1	Q9DDW4 (/ISA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	Q9DDW4 (/ISA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	O35740 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	O35740 (/ISO)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	1	O35740 (/ISO)

Functional Families

There are 27 GO terms relating to "molecular function"

There are 165 GO terms relating to "biological process"

There are 12 GO terms relating to "cellular component"