The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Zinc finger, CCHC-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 49: Zinc finger protein GIS2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
7 P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P53849 (/IPI) P53849 (/IPI) P53849 (/IPI) P53849 (/IPI) P53849 (/IPI) P53849 (/IPI) P53849 (/IPI)
Translation regulator activity GO:0045182
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cytoplasmic translation GO:2000767
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA) P53849 (/HDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)
Polysomal ribosome GO:0042788
A ribosome bound to mRNA that forms part of a polysome.
7 P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA) P53849 (/IDA)
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