The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Zinc finger, CCCH-type
".
FunFam 4: roquin-1 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 24 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
4 | P0C090 (/ISS) Q4VGL6 (/ISS) Q6NUC6 (/ISS) Q9VV48 (/ISS) |
|
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
|
4 | Q4VGL6 (/IDA) Q5TC82 (/IDA) Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | Q5TC82 (/HDA) Q9HBD1 (/HDA) Q9HBD1 (/HDA) |
|
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
3 | Q5TC82 (/IDA) Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
3 | P0C090 (/ISS) Q4VGL6 (/ISS) Q6NUC6 (/ISS) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | Q5TC82 (/IDA) Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P0C090 (/IPI) Q4VGL6 (/IPI) Q5TC82 (/IPI) |
|
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
|
3 | P0C090 (/ISS) Q5TC82 (/ISS) Q6NUC6 (/ISS) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q9HBD1 (/ISM) Q9HBD1 (/ISM) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
Showing 1 to 10 of 24 entries
There are 54 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
4 | P0C090 (/ISS) Q4VGL6 (/ISS) Q6NUC6 (/ISS) Q9VV48 (/ISS) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
3 | Q5TC82 (/IDA) Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
Nuclear-transcribed mRNA catabolic process GO:0000956
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
3 | Q4VGL6 (/ISS) Q5TC82 (/ISS) Q6NUC6 (/ISS) |
|
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
3 | Q5TC82 (/ISS) Q9HBD1 (/ISS) Q9HBD1 (/ISS) |
|
Negative regulation of T-helper 17 cell differentiation GO:2000320
Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.
|
3 | Q5TC82 (/ISS) Q9HBD1 (/ISS) Q9HBD1 (/ISS) |
|
Regulation of miRNA metabolic process GO:2000628
Any process that modulates the frequency, rate or extent of miRNA metabolic process.
|
3 | Q5TC82 (/ISS) Q9HBD1 (/ISS) Q9HBD1 (/ISS) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
2 | Q9HBD1 (/IMP) Q9HBD1 (/IMP) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
2 | P0C090 (/ISO) Q4VGL6 (/ISO) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
|
2 | Q5TC82 (/ISS) Q6NUC6 (/ISS) |
|
B cell homeostasis GO:0001782
The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
|
2 | P0C090 (/IGI) Q4VGL6 (/IGI) |
Showing 1 to 10 of 54 entries
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
4 | A0A024R899 (/IDA) A0A024R899 (/IDA) Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
2 | Q5TC82 (/ISS) Q6NUC6 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
2 | Q4VGL6 (/IDA) Q9VV48 (/IDA) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
2 | Q5TC82 (/ISS) Q6NUC6 (/ISS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9HBD1 (/IDA) Q9HBD1 (/IDA) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
1 | Q4VGL6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q4VGL6 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P0C090 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P0C090 (/ISO) |
Showing 1 to 10 of 11 entries
