View in Gene3D

CATH Superfamily 3.90.640.10

ATPase, substrate binding domain, subdomain 4

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Actin; Chain A, domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Actin, muscle
4826 - - 92.6
2
Heat shock 70 kDa
3976
3D
 3gl1B04 - 98.1
3
Molecular chaperone DnaK
2817
3D
 4kboA04 - 98.6
4
Heat shock 70 kDa protein 4
1344
3D
 3d2fC04 - 99.7
5
Actin-related protein 2
1182
3D
 4jd2B03 - 90.8
6
Actin-related protein 3
ARP3
1067
3D
 3dwlB03 - 95.8
8
alpha-centractin isoform X1
380
3D
 6f1uF03 - 85.8
7
Actin like 7B
356 - - 98.3
9
Actin-like 6A, isoform CRA_a
309 - - 92.8
10
heat shock 70 kDa protein 14
280 - - 97.3
11
Heat shock protein family A
Hsp70
278 - - 43.2
12
Hypoxia up-regulated protein 1
252 - - 86.0
13
Chaperone protein HscA
205 - - 77.3
47
Actin, alpha skeletal muscle
198
3D
 5wfnB03 - 52.5
14
Putative actin-related protein 6
192 - - 95.0
134
Heat shock cognate 71 kDa protein
165
3D
 4j8fA03 - 74.5
15
Actin-like protein
152 - - 70.7
16
ARP5 actin-related protein 5 homolog
128 - - 97.0
17
Actin-related protein 10 homolog
110 - - 80.9
18
Chromatin remodeling complex subunit
96 - - 73.2
19
ARP5 actin-related protein 5 homolog
89 - - 67.0
20
Actin-related protein 8
78 - - 48.0
21
Heat shock protein 14
65 - - 95.2
22
heat shock 70 kDa protein 13
62 - - 45.5
23
Hsp70 chaperone
BiP
54
3D
 4gniB04 - 84.4
24
Molecular chaperone HscC
45 - - 38.5
25
Chromatin remodeling complex subunit
Arp5
40 - - 84.2
26
Actin-related protein 7
39 - - 95.6
27
Actin like 8
38 - - 88.6
28
Actin-related protein 4
37 - - 86.4
29
Heat shock protein 110
36 - - 97.5
30
Heat shock protein HSP70
35 - - 85.5
31
Actin-related protein 4
34 - - 36.6
32
heat shock 70 kDa protein 13
34 - - 68.0
33
Heat shock 70 kDa protein
32 - - 97.2
34
Actin-related protein 5
31 - - 72.3
35
Actin-related protein 8
30 - - 85.5
36
Actin-like protein ARP6
28 - - 73.5
37
Heat shock 70 kDa protein 13
27 - - 40.8
58
Heat shock 70 kDa protein
27
3D
 5fpnB04 - 56.2
61
Actin-related protein 4
24
3D
 5nbnB03 - 40.1
38
Actin, putative
24 - - 9.0
39
Hsp70 family chaperone Lhs1/Orp150
23 - - 85.9
40
Actin-like protein ARP6
23 - - 85.5
41
Actin-related protein 6
23 - - 71.6
42
Heat shock 70 kDa protein 8
22 - - 80.3
43
AGAP008687-PA-like protein
21 - - 83.7
44
Actin-related protein 9
21 - - 73.4
55
Actin-related protein 8
20
3D
 5nbnF02 - 81.4
46
Actin-like protein, putative
20 - - 6.3
45
Actin-related protein 8
20 - - 45.7
48
Heat shock protein 110
17 - - 2.4
49
Putative actin-related protein
17 - - 16.4
50
Actin, cytoskeletal 3
16 - - 70.8
51
Actin-related protein, putative
16 - - 6.3
52
Actin
15 - - 0.0
53
Chaperone DnaK
15 - - 9.6
54
Actin-like ATPase domain-containing protein
15 - - 59.0
56
Heat shock 70 kDa protein 4L
14 - - 21.6
57
Actin-related protein 6
14 - - 77.3
60
Actin-related protein 5
13 - - 50.7
59
Actin-like protein
13 - - 0.0
63
Chromatin remodeling and histone acetyltransferase complexes subunit putative
12 - - 41.7
62
Lhs1p
12 - - 44.5
71
Actin-related protein 7
12
3D
 5tgcD03 - 0.0
64
Actin-like protein, putative
12 - - 10.0
65
Heat shock protein
12 - - 20.2
68
Chaperone protein HscA homolog
11 - - 1.7
69
Actin-related protein 6
11 - - 68.3
70
DnaK protein
11 - - 97.4
66
Actin-related protein 8
11 - - 38.4
67
Actin-related protein 2
11 - - 16.2
76
Cytosolic heat shock protein 70, putative
10 - - 2.9
74
Stress-seventy subfamily Q protein
10 - - 8.5
75
Heat shock 70 kDa protein
10 - - 35.7
72
Conserved hypothetical proline rich protein
10 - - 0.0
73
Unplaced genomic scaffold supercont1.11, whole genome shotgun sequence
10 - - 19.8
78
Conserved hypothetical proline and threonine rich protein
9 - - 0.0
80
Actin-like protein, putative
9 - - 0.0
77
Actin-like protein 2
9 - - 15.8
79
Chaperone protein HscA homolog
9 - - 11.5
82
Actin 2 isoform 1
8 - - 97.1
81
Actin-related protein RO7, putative
8 - - 72.0
84
Related to ARP5-Actin-related protein
8 - - 16.4
83
Protein CBG05834
8 - - 13.5
85
Actin-like protein, putative
8 - - 5.0
86
Actin-related protein 5
8 - - 58.7
87
Actin-like ATPase domain-containing protein
8 - - 41.3
89
Heat shock protein family A
Hsp70
7 - - 51.4
91
Uncharacterized protein
7 - - 11.5
92
Actin-related protein 8
7 - - 3.6
99
Heat shock protein 70 family protein
7 - - 0.0
90
Chaperone protein DNAK, putative
7 - - 2.9
100
Putative actin-like protein
7 - - 40.8
93
Hsp70 protein/TPR repeat/Tetratricopeptide repeat, putative
7 - - 12.8
96
Heat shock 70 kDa protein
7 - - 12.5
94
Actin, putative
7 - - 3.5
95
Actin-related protein 3, putative
7 - - 3.3
98
Actin-related protein 5
7 - - 46.0
97
Molecular chaperone HscC
7 - - 9.0
88
Actin-related protein 8
7 - - 80.9
105
Heat shock protein 70, putative
6 - - 0.0
102
Actin, putative
6 - - 2.7
103
Actin, putative
6 - - 0.0
101
105/110 kDa heat shock protein/ nucleotide-binding domain
6 - - 5.4
106
Heat shock protein 70, putative
6 - - 5.6
107
Actin-57B-like Protein
6 - - 72.8
104
Heat shock protein 70, putative
6 - - 1.4
112
Actin, putative
5 - - 2.2
209
Cell division protein FtsA
5
3D
 4a2bA04 - 0.0
111
Heat shock protein, putative
5 - - 4.0
113
Actin-like ATPase domain-containing protein
5 - - 0.0
110
Chaperone protein DNAK, putative
5 - - 0.0
118
Actin, gamma 2, smooth muscle, enteric
5 - - 17.7
116
Heat shock protein 70 putative
5 - - 8.0
108
Actin-related protein 8
5 - - 8.3
117
Heat shock protein 70, putative
5 - - 0.0
109
Actin-Related Proteins
5 - - 64.1
115
Uncharacterized protein
5 - - 13.5
114
Chaperone protein HscA homolog
5 - - 4.7
128
Brahma associated protein 55kD
4 - - 9.7
132
Uncharacterized protein
4 - - 86.5
129
Actin-related protein 6
4 - - 6.6
124
Heat shock protein 70 putative
4 - - 0.0
131
DnaK protein
4 - - 87.1
119
ARP5 actin related protein 5 homolog
4 - - 39.2
125
Actin related protein 3, putative
4 - - 0.0
126
Heat shock protein 70, putative
4 - - 0.0
127
Actin
4 - - 0.0
120
Heat shock protein 70, putative
4 - - 1.5
121
Actin-like ATPase domain-containing protein
4 - - 3.9
130
Actin-related protein 3, putative arp3
4 - - 10.9
122
WGS project CABT00000000 data, contig 2.6
4 - - 4.3
123
Actin-related protein 8
4 - - 8.2
142
Actin, putative
3 - - 0.0
149
Actin-like protein, putative
3 - - 5.2
139
Chaperone protein dnaK
3 - - 0.0
148
Heat shock 70 kDa protein 14
3 - - 6.9
141
Heat shock protein 70 homolog LHS1, putative
3 - - 4.9
144
Actin-like protein, putative
3 - - 0.0
143
Heat shock protein 70
3 - - 10.4
133
SWI/SNF and RSC complexes subunit arp42
3 - - 80.8
153
Endoplasmic reticulum chaperone BiP
3 - - 64.4
136
Uncharacterized protein
3 - - 5.0
137
Uncharacterized protein
3 - - 4.6
154
Luminal-binding protein 2
3 - - 24.6
147
Actin, putative
3 - - 0.0
135
Uncharacterized protein
3 - - 15.5
145
Actin, putative
3 - - 3.8
152
Uncharacterized protein
3 - - 50.8
146
Actin-related protein 3-1
3 - - 1.2
151
Actin-like protein, putative
3 - - 0.0
138
AGAP004488-PA
3 - - 7.6
140
Related to glucose regulated stress protein, HSP70-like
3 - - 9.7
150
Actin
3 - - 4.4
191
Protein-vacuolar targeting-related protein, putative
2 - - 0.0
170
Actin-related protein 8
2 - - 0.0
207
Uncharacterized protein
2 - - 39.6
184
Actin-related protein
2 - - 0.0
181
AaceriACR184Cp
2 - - 3.1
158
ARP1 actin related protein 1 homolog B
2 - - 49.4
165
Uncharacterized protein
2 - - 0.0
168
Actin-related protein 5
2 - - 0.0
178
Actin4-1
2 - - 5.7
192
Actin-related protein 4
2 - - 0.0
199
Actin, putative
2 - - 0.0
183
Actin family
2 - - 0.0
157
Cysteinyl-tRNA synthetase, putative
2 - - 51.4
204
Putative heat shock 70 kDa protein 14
2 - - 0.0
179
Uncharacterized protein
2 - - 0.0
193
YALI0B10538p
2 - - 0.0
177
actin isoform X1
2 - - 0.0
205
Protein CBG03751
2 - - 8.4
163
Actin-related protein 4
2 - - 3.4
186
Actin7-2
Actin-related protein
2 - - 7.4
156
Actin-related protein 8
2 - - 46.9
196
Uncharacterized protein
2 - - 3.2
194
Actin-related protein 4
2 - - 0.0
171
Hsp70 protein-domain-containing protein
2 - - 0.0
176
Uncharacterized protein
2 - - 1.0
166
Uncharacterized protein
2 - - 0.0
185
Actin related protein
2 - - 0.0
180
Actin, putative
2 - - 0.0
187
Uncharacterized protein
2 - - 1.2
155
Uncharacterized protein
2 - - 4.5
175
Uncharacterized protein
2 - - 0.0
198
Actin, gamma
2 - - 9.2
202
Heat shock 70 kDa protein 14
2 - - 0.0
200
Uncharacterized protein
2 - - 7.1
161
Actin-related protein 8
2 - - 0.0
195
Uncharacterized protein
2 - - 0.0
174
Actin-related protein 10
2 - - 38.0
188
Uncharacterized protein
2 - - 0.0
203
Heat shock 70 kDa protein 14
2 - - 1.5
164
Os08g0369300 protein
2 - - 2.4
160
Heat shock protein70 mitochondrial putative
2 - - 0.0
189
Molecular chaperone DnaK
2 - - 0.0
182
Actin-related protein 10
2 - - 0.0
167
Actin-related protein 6
2 - - 0.0
173
Actin family protein
2 - - 40.8
206
Predicted protein
2 - - 38.4
197
Actin, alpha 1, skeletal muscle
2 - - 7.9
208
Actin-related protein 5-like protein
2 - - 50.5
159
Heat shock protein 70 putative
2 - - 57.6
162
Actin-related protein 8
2 - - 14.0
201
Uncharacterized protein
2 - - 0.0
169
Heat shock protein family A
Hsp70
2 - - 0.0
190
Actin-related protein 5
2 - - 23.7
172
Uncharacterized protein
2 - - 4.2
272
Actin-like protein arp10
1 - - 0.0
294
Immunoglobulin heavy chain binding protein, putative
1 - - 0.0
262
Heat shock protein 70D
1 - - 0.0
232
Actin-related protein 4
1 - - 0.0
225
Predicted protein
1 - - 0.0
278
Predicted protein
1 - - 0.0
222
Uncharacterized protein
1 - - 0.0
217
Uncharacterized protein
1 - - 0.0
281
Predicted protein
1 - - 0.0
252
Actin-related protein 8
1 - - 0.0
224
Uncharacterized protein
1 - - 0.0
279
Uncharacterized protein
1 - - 0.0
263
Actin family protein
1 - - 0.0
293
Heat shock protein, putative
1 - - 0.0
267
HSP70 domain-containing protein
1 - - 0.0
233
Uncharacterized protein
1 - - 0.0
280
Actin-like protein arp5
1 - - 0.0
273
Actin-like protein 3, putative
1 - - 0.0
253
Uncharacterized protein
1 - - 0.0
258
Actin-related protein 2
1 - - 0.0
248
Endoplasmic reticulum chaperone BiP
1 - - 0.0
236
Uncharacterized protein
1 - - 0.0
234
ALP3
1 - - 0.0
288
Chromosome 10, whole genome shotgun sequence
1 - - 0.0
260
Uncharacterized protein
1 - - 0.0
227
Uncharacterized protein
1 - - 0.0
264
Actin family protein
1 - - 0.0
259
Actin-17
1 - - 0.0
249
HSP70-like protein
1 - - 0.0
214
Heat shock protein 70 homolog lhs1
1 - - 0.0
283
Uncharacterized protein
1 - - 0.0
226
Uncharacterized protein
1 - - 0.0
244
Actin-related protein 4
1 - - 0.0
237
Uncharacterized protein
1 - - 0.0
235
Uncharacterized protein
1 - - 0.0
265
Heat shock protein, Hsp70 family
1 - - 0.0
256
Actin-like protein 4
1 - - 0.0
215
Actin-related protein 7
1 - - 0.0
270
Uncharacterized protein
1 - - 0.0
261
Predicted protein
1 - - 0.0
282
Uncharacterized protein
1 - - 0.0
285
Predicted protein
1 - - 0.0
246
AGR099Cp
1 - - 0.0
212
Actin-Related Proteins
1 - - 0.0
257
Uncharacterized protein
1 - - 0.0
229
Uncharacterized protein
1 - - 0.0
284
Actin-related protein 3
1 - - 0.0
247
Actin-related protein 8
1 - - 0.0
289
DnaK protein
1 - - 0.0
290
DnaK protein
1 - - 0.0
210
Uncharacterized protein
1 - - 0.0
271
Actin-like protein 3
1 - - 0.0
242
Uncharacterized protein
1 - - 0.0
254
Actin-related protein 2
1 - - 0.0
213
Uncharacterized protein
1 - - 0.0
243
Uncharacterized protein
1 - - 0.0
228
Uncharacterized protein
1 - - 0.0
268
Uncharacterized protein
1 - - 0.0
238
Uncharacterized protein
1 - - 0.0
211
Uncharacterized protein
1 - - 0.0
218
Uncharacterized protein
1 - - 0.0
221
Actin-like protein 1-1
1 - - 0.0
287
Chromosome 10, whole genome shotgun sequence
1 - - 0.0
255
Actin family protein
1 - - 0.0
274
DnaK protein
1 - - 0.0
250
Actin-related protein 8
1 - - 0.0
276
Uncharacterized protein
1 - - 0.0
240
Uncharacterized protein
1 - - 0.0
230
Uncharacterized protein
1 - - 0.0
239
Heat shock protein 70
HSP70
1 - - 0.0
269
Uncharacterized protein
1 - - 0.0
219
Actin-related protein 10
1 - - 0.0
220
Actin-related protein 8
1 - - 0.0
286
Uncharacterized protein
1 - - 0.0
275
Mitochondrial-type heat shock protein70 putative
1 - - 0.0
251
Uncharacterized protein
1 - - 0.0
245
Uncharacterized protein
1 - - 0.0
292
Uncharacterized protein
1 - - 0.0
291
DnaK protein
1 - - 0.0
241
Predicted protein
1 - - 0.0
266
Uncharacterized protein
1 - - 0.0
231
Uncharacterized protein
1 - - 0.0
223
Actin-related protein 8
1 - - 0.0
216
Uncharacterized protein
1 - - 0.0
277
Uncharacterized protein
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...