The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22: Histo-blood group ABO system transferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetyllactosaminide 3-alpha-galactosyltransferase. [EC: 2.4.1.87]
UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D- glucosaminyl-R = UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl- (1->4)-beta-N-acetylglucosaminyl-R.
  • Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo- alpha(1)-acid glycoprotein and N-acetyllactosamine (beta-D- galactosyl-1,4-N-acetyl-beta-D-glucosamine), but not on 2'-fucosylated-N-acetyllactosamine.
  • The non-reducing terminal N-acetyllactosamine residues of glycoproteins can also act as acceptor.
  • Formerly EC 2.4.1.124 and EC 2.4.1.151.
24 A0A4Z3 A1YGR5 A1YGR6 A2AUQ7 G3V9Q9 L8HQ30 L8HQ30 P14769 P14769 P23336
(14 more...)
Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase. [EC: 2.4.1.40]
UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl- (1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl- (1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.
  • Acts on blood group substance H.
  • Can use a number of 2-fucosyl-galactosides as acceptors.
7 A0A089QDC1 A0A089QDC1 P16442 P16442 P38649 Q8CFC4 Q9ET32
Fucosylgalactoside 3-alpha-galactosyltransferase. [EC: 2.4.1.37]
UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
  • Acts on blood group substance, and can use a number of 2-fucosyl- galactosides as acceptors.
7 A0A089QDC1 A0A089QDC1 P16442 P16442 P38649 Q8CFC4 Q9ET32
Globoside alpha-N-acetylgalactosaminyltransferase. [EC: 2.4.1.88]
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-D-galactosaminyl-(1->3)-D- galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-D-galactosaminyl-(1->3)-N-acetyl-D-galactosaminyl-(1->3)-D- galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide.
    2 Q8VI38 Q95158
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