The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Creatinase/methionine aminopeptidase superfamily
".
FunFam 3: Methionine aminopeptidase 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Aminopeptidase activity GO:0004177
Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
Metalloexopeptidase activity GO:0008235
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
3 | P50579 (/HDA) P50579 (/HDA) P50579 (/HDA) |
|
Aminopeptidase activity GO:0004177
Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
|
3 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Metalloexopeptidase activity GO:0008235
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
3 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Aminopeptidase activity GO:0004177
Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O08663 (/IPI) O08663 (/IPI) |
|
Metalloexopeptidase activity GO:0008235
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
2 | Q38C98 (/ISM) Q4QCC5 (/ISM) |
|
Exopeptidase activity GO:0008238
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.
|
2 | H1UBK1 (/IDA) Q9U2V9 (/IDA) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
Peptidyl-methionine modification GO:0018206
The modification of peptidyl-methionine.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
N-terminal protein amino acid modification GO:0031365
The alteration of the N-terminal amino acid residue in a protein.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
3 | A0A0R4IUB7 (/IGI) Q6NUX5 (/IGI) Q7SXK1 (/IGI) |
|
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
3 | A0A0R4IUB7 (/IMP) Q6NUX5 (/IMP) Q7SXK1 (/IMP) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
3 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Peptidyl-methionine modification GO:0018206
The modification of peptidyl-methionine.
|
3 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Regulation of rhodopsin mediated signaling pathway GO:0022400
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
|
3 | P50579 (/TAS) P50579 (/TAS) P50579 (/TAS) |
|
N-terminal protein amino acid modification GO:0031365
The alteration of the N-terminal amino acid residue in a protein.
|
3 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
3 | A0A0R4IUB7 (/IMP) Q6NUX5 (/IMP) Q7SXK1 (/IMP) |
|
Hematopoietic stem cell differentiation GO:0060218
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
3 | A0A0R4IUB7 (/IMP) Q6NUX5 (/IMP) Q7SXK1 (/IMP) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
2 | H1UBK1 (/IDA) Q9U2V9 (/IDA) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
2 | Q38C98 (/ISM) Q4QCC5 (/ISM) |
|
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
|
2 | H1UBK1 (/IMP) Q9U2V9 (/IMP) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
2 | Q56Y85 (/TAS) Q56Y85 (/TAS) |
|
Peptidyl-methionine modification GO:0018206
The modification of peptidyl-methionine.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
N-terminal protein amino acid modification GO:0031365
The alteration of the N-terminal amino acid residue in a protein.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
N-terminal protein amino acid modification GO:0031365
The alteration of the N-terminal amino acid residue in a protein.
|
2 | Q9FV49 (/TAS) Q9FV49 (/TAS) |
|
Protein initiator methionine removal involved in protein maturation GO:0035551
Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.
|
1 | O60085 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | A0A140VJE3 (/IDA) A0A140VJE3 (/IDA) A0A140VJE3 (/IDA) F8VQZ7 (/IDA) F8VQZ7 (/IDA) F8VQZ7 (/IDA) P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | A0A140VJE3 (/IDA) A0A140VJE3 (/IDA) A0A140VJE3 (/IDA) F8VQZ7 (/IDA) F8VQZ7 (/IDA) F8VQZ7 (/IDA) P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P50579 (/IDA) P50579 (/IDA) P50579 (/IDA) Q38C98 (/IDA) Q56Y85 (/IDA) Q56Y85 (/IDA) Q9FV49 (/IDA) Q9FV49 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O08663 (/ISS) O08663 (/ISS) P38062 (/ISS) Q7SXK1 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | O08663 (/ISO) O08663 (/ISO) Q4QCC5 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P50579 (/TAS) P50579 (/TAS) P50579 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O08663 (/ISO) O08663 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O60085 (/HDA) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q55C21 (/HDA) |
